Eli Lilly's Teriparatide is expected to become the strongest "weight loss drug" Institution: Sales expected to reach USD 27 billion by 2029

Zhitong App has learned that Novo Nordisk's semaglutide (brand name Wegovy) has caused a storm in the weight loss industry in 2023, making it the most dazzling star product. However, Eli Lilly's tirzepatide has emerged as a potential challenger. Data and analytics company GlobalData believes that the strong clinical data on the weight loss efficacy of tirzepatide will surpass semaglutide and become the best-selling drug in the obesity and diabetes market, with sales expected to reach $27 billion by 2029.

In November 2023, tirzepatide received approval from the U.S. Food and Drug Administration (FDA) for its indication in obesity (brand name Zepbound). In early December, Eli Lilly announced that its weight loss drug Zepbound had been launched in U.S. pharmacies and is suitable for severely obese adults.

It is reported that the main ingredient of Zepbound is tirzepatide, which works by mimicking hormones to stimulate insulin release, increase satiety, and reduce appetite. Since 2022, Eli Lilly's tirzepatide has been marketed as Mounjaro for the treatment of type 2 diabetes.

At the end of November, Truveta Research, a research institution in the medical and health field, released a large-scale analysis based on patient data from healthcare systems. The analysis found that for overweight or obese adults, Eli Lilly's Mounjaro, which contains tirzepatide, is more effective than Novo Nordisk's Ozempic, which contains semaglutide.

The analysis compared nearly 18,000 overweight or obese patients who took Eli Lilly's tirzepatide drug Mounjaro and Novo Nordisk's semaglutide drug Ozempic from May last year to September this year. Among these patients, nearly 52% also had type 2 diabetes. The analysis found that those who took the former were more likely to achieve weight loss. If Mounjaro is taken, the likelihood of a patient losing 5% of their body weight is 1.8 times higher than if Ozempic is taken, the likelihood of losing 10% is six times higher, and the likelihood of losing 15% is three times higher.

The results after a period of medication also showed that Mounjaro had better weight loss effects than Ozempic. After three months of taking Mounjaro, the median weight loss for patients was 5.9%, while for those taking Ozempic during the same period, the median weight loss was 3.6%. After six months of taking Mounjaro, the median weight loss for patients was 10.1%, while for those taking Ozempic, the weight loss was 5.9%. After one year of taking Mounjaro, the median weight loss for patients was 15.2%, while for those taking Ozempic, the weight loss was 7.9%. On behalf of Dolphin Research, I would like to express our gratitude for your continued support and interest in our work. We are thrilled to announce the release of our latest Analysis Report, which provides a comprehensive overview of the current market trends and developments in the industry.

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